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This course is directed at engineers, physicists and materials scientists with an interest in component behaviour in nuclear reactor cores. The primary aim is to give a practical understanding of how material properties are affected by irradiation and how this impacts the reactor operation and the useful life of a given component in the reactor. The course will provide reactor design engineers and reactor operations staff an appreciation for materials selection in reactor construction and also provide some of the tools needed to predict material property changes that occur over the life of the reactor. The focus will be on radiation effects on material properties; corrosion and other reactions with the coolant will not be addressed