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The Gordon Research Conference on Organellar Channels and Transporters, held for the 3rd time in 2019, is dedicated to ion channels and primary or secondary transporters from intracellular organelles in animals, plants, and yeasts. Organelles covered include, but are not limited to, endosomes, lysosomes, vacuoles, mitochondria, chloroplasts, the nucleus, endoplasmic reticulum, Golgi, secretory vesicles and the primary cilium. The field of intracellular channels and transporters recently gained momentum thanks to the breakdown of several technical barriers. While the identification of novel intracellular channels and transporters, and the characterization of their structures and mechanisms, is producing exciting discoveries, new themes have emerged, such as their regulation by unanticipated signals, the dynamic nature of organelle metabolomes and the crosstalk between distinct organelles in integrated cellular responses. This conference aims to bring together investigators working in fields from plant biology to human diseases who might not otherwise interact. The talks will focus on the above recent developments at the molecular, cellular and organismal levels and will include new, unpublished work according to the guiding principles of a Gordon Conference. The program will include junior as well as senior investigators. Several abstracts will be selected for oral presentation and one student or postdoc participating in the associated Gordon Research Seminar (GRS) will be selected for an invited talk during the keynote session. In addition, the programmed discussion time, afternoon free time and poster sessions as well as meals will provide abundant time for interaction among the diverse groups.