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Constant reform and innovations have been occurring in medical practice and education globally for the past decades. These have been as a result of advances in medical practice worldwide. In addition, patients have become more informed about their health, and these have resulted in increased in demands and expectations, thereby bringing about the changing roles of the doctors and healthcare workers in society. There are now needs for healthcare workers to be more involved in teaching and research, as well as in patient care. Hence the conference on ‘Medical Practice in the 21st Century’ will embrace many topics on the various issues affecting medical practice, research and education.