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More than 1,000 researchers and clinicians are expected to attend the Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) annual Forum Feb. 28-March 2, 2019, in Dallas, Texas. Themed “Precision Medicine Approaches for MS: Scientific Principles to Clinical Application,” this CME-accredited meeting stands apart from many traditional medical meetings by offering a single track of scientific and clinical presentations in an interactive environment. Young investigators are selected for platform presentations based on submitted abstracts. A record number of abstracts were received during the regular abstract submission period, setting the stage for more than 300 posters to share investigative results.