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The focus of the conference will be on the transition from understanding and predicting properties towards the rational design of material systems that qualify for being complex and adaptive. These are not simple materials, but systems that possess properties, which so far are only known for living organisms or man-controlled machines like robots. We believe it is very timely to discuss together with physicists, chemists and also interested researchers from life science the state of the art and the particular challenges given by the gap between assembly of molecules to materials and developing molecular systems that can actively interact with feedback mechanisms and have the ability to perform work. Participants can expect a highly inspiring program with an excellent set of speakers.