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The annual meeting of the European Cytoskeletal Forum, this year organised as a focussed meeting of the Biochemical Society, UK, brings together new and established scientists from a wide range of disciplines, including biochemists, biophysicists and cell biologists to discuss recent advances in cell migration and adhesion. Topics covered include actin dynamics, cytoskeleton-membrane interactions, signalling in motility, adhesion, and migration during development and disease.