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The purpose of this five day workshop is to provide a foundation of knowledge to those beginning to investigate mitochondrial function and biogenesis or those simply interested in understanding these essential subcellular organelles. Participants will learn of the important metabolic reactions occurring within the mitochondria and how nuclear and mitochondrial DNA lesions can result in a wide variety of mitochondrialders. The workshop will include a combination of lectures and hands-on laboratory experiments designed to familiarize the participants with the skills necessary to work with these organelles.