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Recent advances in whole genome analyses has vastly improved our appreciation of the extensive repertoire of noncoding RNAs, including initially the well-known small microRNAs (miRNAs), and more recently, the long noncoding RNAs (lncRNAs). While miRNA-target interactions appear to be important in control of post-transciptional levels, lncRNAs appear to have a diverse array of functions including regulation of transcription, mRNA processing and post transcriptional control. Thus, the current state of the art transcriptional profiling should include technologies for the analyses of protein coding mRNA, miRNAs and lncRNAs.In this hands-on training workshop, participants will learn the latest information about miRNA and the use of miRNA as a diagnostic tool.