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It is our great pleasure to announce that the next meeting of the International Study Group for Systems Biology (ISGSB, formerly BTK) will be held in Jena from October 4A¢a‚¬a€oe7, 2016 and, thus, for the first time, in Germany. In addition, there will be special scientific and social activities by the Y(oung)SGSB (early career ISGSB). The biennial ISGSB meetings are devoted to advancing the biological sciences by exploring the interplay between mathematical modelling, computer simulation and wet-lab experiments. ISGSB had dealt with topics of Systems Biology even before that term was coined. Models can be presented and discussed in more detail than usual at other conferences.