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Medicinal Chemistry of Boron Compounds Conference

4th October 2015 - 7th October 2015
Oropesa, Spain


We are proud to add to our conference listing the inaugural Medicinal Chemistry of Boron Compounds Conference which shall be taking place 4th October – 7th October 2015 at the Parador de Oropesa in Spain. The pharmacological uses of boron compounds have been known for several decades. However, recent progress in the bioorganic chemistry of boron is closely related to the discovery of boron-containing compounds as prospective drugs. While first developments of the medicinal chemistry of boron were stipulated by applications in boron neutron capture therapy (BNCT) of cancers, more recently it was found that some boron analogues of amino acids and their derivatives express hypolipidemic, anti-inflammatory, antiarthitic, antipleurisy, and analgesic properties. The knowledge accumulated during the past decades on the chemistry and biology of bioorganic boron compounds laid the foundation for the emergence of a new area of study and application of boron compounds as lipophilic pharmacophores and modulators of biologically active molecules; for example, carborane-containing compounds inhibit HIV replication, show anticancer activity, modulate purinergic receptors, etc. An additional advantage of boron clusters is that they are abiotic and therefore chemically stable in biological environment and usually resistant to catabolism. These and other recent findings clearly show that there is still great unexplored potential in medicinal applications of boron-containing compounds. This conference will promote the development of new boron-containing drugs and materials for molecular medical diagnostics by bringing together renowned experts in the field of medicinal chemistry of boron compounds.

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