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Based on their broad biological activity and their involvement in many diseases the 2018 Chemotactic Cytokines Gordon Research Conference (GRC) will cover many aspects of the chemokine system, as denoted in the session titles of this meeting. This includes sensing of chemokines; chemokines in cell migration, positioning, and organ organization; atypical chemokine receptors; stromal and lymphatic cells as chemokine producers; and crystal structures and therapeutic targeting of the chemokine system.