Abstract

This conference will facilitate interactions in biomedical research using cutting-edge omics technologies and integrative methods to address the precision medicine challenge that most human disease has complex etiology with involvement of multiple genetic, dietary, microbiome, environmental and behavioral factors. Oxidative stress is a prime contributing mechanism in many disease processes, thereby creating opportunity for vibrant interactions among experts using different technologies to study different oxidative disease processes. The running theme throughout will be redox mechanisms in disease, with experts selected based upon their use of advanced omics methods to address redox mechanisms of complex diseases. Sessions are designed to be integrative in nature, bringing together complementary omics platforms and spanning basic, translational and clinical applications. Speakers will be challenged to be prospective in scope, encompassing prevention as well intervention and remediation in the natural course of disease. The GRC format is particularly well suited to help investigators trained in targeted mechanistic research expand their research to incorporate powerful new omics technologies and bioinformatics methods. The new technologies are global in nature, enabling studies to expand controlled hypothesis-driven research to capture largescale responses of the genome, epigenome, transcriptome, proteome, epiproteome, lipidome, glycome, metabolome, microbiome and metallome as well as new omics-level imaging methods. Conversely, the format will facilitate early stage investigators in omics technologies and computational biology to engage their skills toward elucidation of critically important oxidative mechanisms and redox therapeutics. Participants will enjoy presentations by and interactions with outstanding research leaders using the latest omics technologies to address oxidative disease mechanisms and interventions using complex systems approaches.