Activating an estrogen receptor can stop pancreatic cancer cells from growing: Penn study shows GPER activation in mice can also make tumors more visible to immune system

Activating the G protein-coupled estrogen receptor (GPER) -- a receptor found on the surface of many normal and cancer tissues -- has been shown to stop pancreatic cancer from growing, but may also make tumors more visible to the immune system and thus more susceptible to modern immunotherapy. Researchers observed the effects of GPER activation in human and mouse pancreatic cancer models.



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