cancerresearch

Cancer Research

1 Years ago

Eat 'em up: Next-generation therapeutic helps immune cells detect, destroy cancer: Supramolecule provides a double whammy to knock out cancer's 'eat-me-not' signaling, keep macrophages on the attack

Researchers have found that cancer cells evade destruction by macrophages in two ways -- by converting cells to become docile, M2 macrophages, and by sending out an 'eat me not' signal that tricks M1 macrophages into letting them be. Investigators have developed a therapeutic that delivers a double whammy to knock out both mechanisms.

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