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Recording every cell's history in real-time with evolving genetic barcodes: New technique enables creation of a full developmental lineage record for cells in vivo

Recording every cell's history in real-time with evolving genetic barcodes: New technique enables creation of a full developmental lineage record for cells in vivo

A new method uses evolving genetic barcodes to actively record the process of cell division in developing mice, enabling the lineage of every cell in a mouse's body to be traced back to its single-celled origin. This approach enables scientists to pinpoint where and when different cells arise and how closely related different cell types are to each other, allowing unprecedented insight into the journey from zygote to adult.

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