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The purpose of PACT 2018 is to bring together researchers from architecture, compilers, applications and languages to present and discuss innovative research of common interest. PACT started as a Data Flow Workshop in conjunction with ISCA 1989 but quickly evolved into a unique venue at the intersection of classical parallel architecture and compilers. Recently, PACT widened its scope to include insights useful for the design of machines and compilers from applications such as, but not limited to, machine learning, data analytics and computational biology.