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The Crystal Growth and Assembly Gordon Research Conference is dedicated to the knowledge and understanding of the fundamental atomic and nanoscale physics and chemistry that are central to the nucleation and growth of crystals for a wide array of technologies. This well-established conference draws researchers from around the world in the fields of physics, chemistry, engineering, materials science, biology, and beyond. Historically, the conference has emphasized concepts rather than specific materials, technologies or growth methods. This focus has attracted scientists with a broad range of specializations, from semiconductor nanowires to biomineralization and from in situ microscopy to multi-scale computer simulations, who find common inspiration in seeing how the general principles of crystal thermodynamics and growth kinetics are applicable to many fields. The 2019 Crystal Growth and Assembly GRC will continue the tradition of a highly interdisciplinary program, highlighting the most recent developments in the field. It will cover topics like nucleation, nonclassical growth, colloidal self-assembly, surface kinetics, nanocrystals, biogenic materials, and bulk crystallization. This year, a particular focus will be on the discussion of new and developing mechanistic understandings of crystallization and assembly spanning a broad range of materials.