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This course is directed at engineers, and materials scientists interested in fuel performance in general and specifically in Zr alloy corrosion and hydrogen pickup mechanisms and performance. The focus will be on explaining the very complicated corrosion and hydrogen pickup mechanisms in an understandable manner. Also, the various parameters impacting corrosion and hydrogen pickup will be covered as well as discuss specific in-reactor cases with abnormal corrosion and hydrogen pickup behaviours and the possible reasons behind the behaviours.