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RNA modifications are ubiquitous in biology and present in all classes of cellular RNAs. Recent studies have shown that RNA modifications are critical to the processing and metabolism of different RNA species, and represent a new mode of post-transcriptional gene expression regulation. This conference brings together world’s experts on RNA modification research with an emphasis on biological function and physiological relevance of RNA modifications. Speakers will discuss functional significances of RNA modifications in cell differentiation and development, human diseases such as cancer, neurobiology, metabolism, and other related subjects.