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At a time when our diabetes knowledge and treatment options have advanced so much, why do clinical outcomes remain suboptimal, with so many patients unable to achieve good control of their disease? The answer is rooted in three challenges: Keeping pace with rapidly advancing options for diabetes care Accounting for a patient’s unique biological, psychological, social, financial, educational, and cultural factors Overcoming structural healthcare barriers, requiring clinical strategies to fit within a particular mold This established Harvard Medical School course offers practical strategies to address these challenges and updates that ensure you can deliver state-of-the-art care for your patients with diabetes.