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Course Directors: Martin Bues, Ph.D.; Samir H. Patel, M.D.; Jason Shen, Ph.D.; and Carlos E. Vargas, M.D. The Mayo Clinic Practical Proton Therapy Seminar and Workshop is designed to provide a focused interactive educational experience on how to implement pencil beam scanning therapy. The seminar includes lectures on the basic principles of proton beam therapy, proton beam clinical trials, and practical discussions through case-based vignettes with experienced proton beam faculty. The interactive workshop allows for faculty to share how proton beam therapy is implemented in our clinic with hands-on demonstrations of patient immobilization at CT simulation, treatment planning and evaluation, image-guided radiation therapy, IGRT and beam delivery, including comprehensive QA. Course attendees are also invited to send a submission for the Poster session, taking place on Friday, January 25th. If you are interested, please email us at firstname.lastname@example.org This program is endorsed by the AAPM.