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Association of Nepalese Mathematicians in America (ANMA), Nepal Mathematical Society (NMS) and mathematics departments of Tribhuvan University and Kathmandu University are jointly organizing the Second International Conference on Applications of Mathematics to Nonlinear Sciences (AMNS-2019) in Pokhara, Nepal, on June 27-30, 2019. The conference provides a forum to a diverse group of scientists in applications of mathematics to natural and health sciences, engineering and finance. Specific areas include differential equations, mathematical biology, computational mathematics, statistics and big data, analysis, topology, algebra, mathematics education, optimization, operations research, quantitative finance, biomedical science, biophysics, and public health. The conference aims to bring together researchers from a variety of disciplines which impact nonlinear analysis and applications in bio- and physical sciences from the southeast Asian countries and around the globe.