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One of the big ideas in modern mathematics is that integers (like 1, 2, 3, 4, 5, ...) in many formal ways behave similarly to polynomial equations (like y = x^2, which defines the parabola). Frequently, and perhaps surprisingly, many questions in mathematics are easier to study for polynomials than for integers. Hence intuition and results for polynomials can tell us about the integers. Commutative algebra lives at the intersection of both perspectives, and one fundamental object of study is polynomials with integer coefficients, this is called the mixed characteristic case. Recently, Yves Andre proved a long standing open conjecture in commutative algebra in this mixed characteristic setting, relying on constructions of Scholze (and then Bhatt gave a simplified proof of the same conjecture). This workshop aims to foster and discuss these and other recent tools, to study some remaining open problems in mixed characteristic. The workshop will bring together a diverse group of researchers from different fields, such as commutative algebra, algebraic geometry, and number theory.