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The International Conference on Numerical Analysis and Optimization will be held in Sultan Qaboos University (SQU), Muscat, Oman on January 6-9, 2020. This is the 5th conference in a series organized every three years since 2008. The purpose of the conference is to bring together worldwide experts to give presentations on novel and advanced applications in their latest work in engineering, science and medicine to facilitate cross-fertilization among various key sectors of pure scientific and applied knowledge. Hopefully, the conference will become the place where prominent scientists, worldwide experts and active researchers gather and meet to stimulate the communication of new innovative ideas and knowledge on new scientific methodologies, promote scientific exchange and discuss possibilities of further cooperation, networking and promotion of mobility of senior and young researchers and research students.