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The PLM series started 15 years ago from an interest to promote the interface between the Life and Physical Sciences in Cambridge. Over the years, PLM has grown from a local meeting to a popular international event that attracts interdisciplinary scientists from all around the world. Since 2018, a new partner has joined PLM: the Turing Centre for Living Systems (CENTURI, Aix-Marseille University, France) and the 2018 PLM symposium took place in Marseille. In 2020, PLM will be back in Marseille for its 15th edition that will take place on October 01 & 02. In addition to an exciting programme presented by renowned international speakers, oral presentations will be selected from the submitted abstracts.