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The Wellcome Trust is pleased to announce the 28th annual Mouse Molecular Genetics conference. This conference is the leading forum for researchers who apply genetics and genomics techniques in the mouse to address fundamental issues in mammalian biology. The Mouse Molecular Genetics conference attracts international participation and promotes the presentation of novel, unpublished research findings. This year’s meeting will showcase the latest developments in genetics, genomics, engineering of the mouse genome, systems analysis and imaging of dynamic molecular and physiological processes.