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The development and maintenance of axons require efficient long-range communication in the nervous system. Axons extend distances ranging from a fraction of a millimeter to more than a meter in humans, lengths that require specialized mechanisms for formation, maintenance and regeneration. Given their extreme polarity and size, axons are particularly vulnerable to the risk of degeneration and dysfunction upon injury or disease.This is a unique meeting that will cover a broad spectrum of the latest developments in axonal research, from development and maintenance, through to survival and repair, in both the central and peripheral nervous system. Additional topics and late-breaking developments will be incorporated via talks selected from abstracts, specifically encouraging participation of young researchers and those new to the field. The multidisciplinary theme and shared focus will facilitate communication from basic to clinical neuroscience, bridging these two communities and creating unique opportunities to synergize and collaborate.