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We are delighted to announce the 68th Annual Meeting of the Society for Reproductive Investigation (SRI) July 6 – 9, 2021 in Boston, MA, USA. For the first time, the 2021 SRI Annual meeting will be held in a hybrid format—providing options for both in-person and virtual attendance! Based on current vaccination rates in the US, levels of projected COVID-19 immunity and achievement of herd immunity, and expected relaxation of restrictions for hotel occupancy, an option for in-person attendance is planned. The theme of the 2021 meeting is, “Navigating the Future for Reproductive Science.” With Irina Burd, MD, PhD, as Program Director, the Program Committee has developed an outstanding program that includes President’s Distinguished Researchers, career development activities, Oral Sessions, invited Mini-Symposia, invited Lunch and Learn Symposia and a Hot Topics Plenary Session. The meeting will feature inspiring talks from two outstanding President’s Distinguished Researcher Awardees: Joan Steitz, PhD, 2018 Lasker-Koshland Awardee from the Yale School of Medicine and Gregg Semenza, MD, PhD, 2019 Nobel Laureate from Johns Hopkins. In addition, Susan Fisher, PhD, the 2020 March of Dimes Developmental Biology Prize Awardee from University of California, San Francisco will deliver an exciting lecture on her research. Several career development activities and networking opportunities will be offered, including Career Development Workshops, “Your Grant in One Page Clinic,” Early and Mid-Career Sessions, and “Connection Corners.” Also NEW this year, the Diversity, Equity, and Inclusion Forum will be held on Thursday, July 8, over the lunch hour, giving all participants an option to attend. To allow all abstract submitters to participate and share their science the poster sessions will be virtual this year. Please watch for a link to the virtual abstract site as the meeting approaches. If selected for a poster, participants will have the option to hang their poster in the poster hall if they wish. If selected for oral presentation, a virtual option will be possible. We understand that COVID-19 may have delayed your research and Late Breaking Abstract submissions for the 2021 Annual Meeting will be open from March 26 to May 7. We have added new abstract categories this year including Women-s Health Disparities and Inequities and COVID-19. The SRI will offer several travel awards for the Annual Meeting for those attending in-person as well as various In Training Investigator and other awards throughout the meeting. The 2021 Annual Meeting will be held in Boston, MA, USA at the Boston Marriott Copley Place. For in-person attendees, SRI will adhere to local requirements regarding masking, occupancy, and social distancing. The SRI leadership strongly encourages all in-person attendees to get vaccinated. As always, the 68th Annual SRI Meeting will be highly collegial and provide a forum for outstanding science and the opportunity for fruitful global networking. On behalf of the SRI Council, Program Committee, and Staff, we are pleased to offer this NEW option for participation! Come in person or connect online to share your science with your friends and colleagues at SRI!