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Dear colleagues, On behalf of the International CTEPH Association (ICA) it is our pleasure to invite you to our International CTEPH Conference (ICC). The organising committee of ICC 2021 had to postpone the conference originally planned for 4-5 June 2021 a second time due to the COVID-19 pandemic. A new date has been set for 10-11 December 2021. The location will remain the same: Hotel Dolce in Bad Nauheim, Germany. In view of the current travel restrictions and regulations the meeting will be held in a hybrid format, meaning that you can participate either in person or virtually. The triennial ICC medical congresses are dedicated exclusively to chronic thromboembolic pulmonary hypertension (CTEPH). The field of CTEPH has seen a remarkable evolution in recent years. Interventional treatment has established itself as standard worldwide, and extensive research is ongoing into the optimal use of existing treatment modalities depending on patient profiles. The programme for the upcoming ICC 2021 covers many aspects of the disease, ranging from pathophysiology and epidemiology, to diagnosis and surgery, interventional treatment, medical and multimodal therapy. The possible influence of the COVID-19 pandemic on CTEPH incidence will be considered and the final session will be devoted to current hot topics in the field. Our goal is to offer a platform for sharing and discussing the latest scientific and clinical developments in CTEPH, to enable an informative and dynamic conference. Take advantage of the early bird registration offer, which can be converted to virtual participation if you are unable to attend in person. We look forward to welcoming you to Bad Nauheim in 2021 – in person, or virtually.