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The congress will address applications of genome editing and gene modulation technologies in a variety of systems. This meeting will develop upon our ongoing RNAi series of conference at Oxford since 2006 and our 1st CRISPR symposium in 2015. The Congress will take an ‘application-based approach’ to its scientific agenda and will include genome editing technologies, such as CRISPR, TALENs and ZNF and gene modulation approaches, such as RNAi and antisense oligos. The Congress will be co-hosted with our 3rd annual Aptamers 2016, 2nd annual Oligos 2016 Oxford and 1st annual Exosome 2016 Oxford and 11th annual RNAi 2016.