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The 15th Biennial Meeting of the International Society for Applied Cardiovascular Biology (ISACB) will convene in Banff, Alberta, Canada, September 7-10, 2016 at the Banff Centre which is nestled on the side of Tunnel Mountain in Banff National Park, a UNESCO World Heritage Site in the heart of the Canadian Rockies. The conference is organized by the International Society for Applied Cardiovascular Biology (ISACB), a professional society founded in 1987. The goal of the conference is to establish a research agenda going forward that will address and resolve barriers to the understanding and translation of discoveries in cardiovascular medicine into therapeutic modalities that improve public health. This conference will provide a forum for cardiovascular researchers working in research laboratories in academia, in industry and in the clinics to convene to disseminate new information in their fields, build relationships with one-another and hopefully renew and establish new collaborations and strategies for translating advancements derived from the understanding of the biology of cardiovascular disease to the care and management of patients. The focus of the conference will be upon translation of basic research relevant to regenerative therapies including stem cells, tissue interactions and cardiovascular biomaterials and novel cardiovascular diagnostics, imaging and therapeutics. A dedicated plenary session will focus upon issues related to regulatory science and commercialization.