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This course provides an integrated approach to comprehending the basis and applications of breast imaging in six distinct sessions. Sessions 1 and 2 will take the attendee through the histopathologic basis for benign and malignant breast disease with imaging correlates. Conventional topics with simplified and novel strategies are presented to both review and advance the practice of mammography and ultrasound, and the alternatives of imaging surveillance. Session 3 focuses on current and evolving concepts in MRI imaging and advanced digital platforms, offering perspectives on different technologies that can be incorporated into every day clinical practice. Sessions 4 and 5 are devoted to issues in breast interventional procedures and breast density; reviewing the topics all practicing radiologists need to know and providing a foundation for management recommendations. Finally, Session 6 will go over the medical and legal issues in breast imaging.