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The combined growth of the biopharmaceutical industry and the globalization of the industry where the products needs to be transported from the origin to the destination at different points requiring controlled temperature to ensure the quality and safety of the products has resulted in numerous challenges for pharmaceutical professionals involved in their procurement, distribution and quality, therefore it is mandatory to understand the best practices for distribution of temperature sensitive products. This is especially important to the GCC as most temperature-sensitive pharmaceuticals are imported and due to the GCC experiencing massive air-cargo growth. It is also imperative that all stakeholders work in closer unison to achieve as few stalls and gaps as possible ensuring a smooth flow from factory to end user thus mitigating risk and ensuring patient safety.