Abstract

We are pleased to announce the 2nd in our series of meetings on mitochondrial disorders and the quest for novel effective therapies. Mitochondrial diseases form the largest group of inherited metabolic disorders, and the past decade has seen major advances in our understanding of the molecular mechanisms involved. Novel therapeutic strategies are being developed based on this new knowledge, and preclinical studies in animal models show great promise. This conference will bring together world leaders in the field of translational mitochondrial medicine in an interactive programme designed to engage and inspire a new generation of mitochondrial researchers, who will harness this new technology to prevent and treat these devastating diseases. The meeting attracts international participants interested in mitochondrial diseases, working in molecular genetics, biochemistry, pathology, and clinical medicine. Scientific sessions - Novel mechanisms of mitochondrial disease - Measuring clinical progression - Disease biomarkers - Precision medicines - Targeted treatment - Current active trials Scientific programme committee Patrick Chinnery University of Cambridge, UK   Marni Falk The Childrena€™s Hospital of Philadelphia, USA  Vamsi Mootha Harvard Medical School, USA   Jan Smeitink Radboud UMC, The Netherlands Anu Suomalainen University of Helsinki, Finland Massimo Zeviani MRC Mitochondrial Biology Unit, Cambridge, UK Confirmed speakers Mary Herbert University of Newcastle, UK Saskia Koene Radboud UMC, The Netherlands Michal Minczuk MRC Mitochondrial Biology Unit, Cambridge, UK Carlos Moraes University of Miami Miller School of Medicine, USA Michael Murphy MRC Mitochondrial Biology Unit, Cambridge, UK Holger Prokisch Technische Universitat Munchen, Germany Elena Rugarli University of Cologne, Germany Luca Scorrano University of Padova, Italy Valeria Tiranti Foundation IRCCS-Neurological Institute C. Besta, Italy Douglas Turnbull University of Newcastle, UK Alex Whitworth MRC Mitochondrial Biology Unit, Cambridge, UK