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Stem cells have the unique properties of both self renewal and differentiation into various lineages. In the last few years, chromatin architecture and noncoding RNAs are emerging as major players in both gene regulation and stem cell differentiation. This conference will cover some of the most recent advances and cutting edge research in the field of chromatin organization, transcription regulation and stem cell biology. We aim to provide a forum in which interdisciplinary discussions will promote cross-collaboration between experts in these areas. Moreover, during the meeting, there will be great opportunities for young scientists to meet the experts in the field.