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Following successful meetings in Boston, Kyoto, San Francisco and Berlin, ICBS presents its Fifth Annual Conference: Translational Chemical Biology. Twenty-two confirmed invited speakers plus 22 registrants selected from submitted abstracts will present oral presentations in nine sessions including infectious disease, cancer, neurodegenerative disorders, regenerative medicine, imaging and biosensors, epigenetics, natural products, lipids, and the human microbiome. Two poster sessions will be held with evening receptions. ICBS will again recognize three early-stage scientists in a Rising Stars of Chemical Biology session. ICBS2016-Madison will create a vibrant forum for the exchange of information on the latest advances in chemical biology and progress toward translation of these findings in important therapeutic areas.