Abstract

The goal of this meeting is to provide attendees with a comprehensive overview of current research on atherosclerosis with a focus on the latest and most exciting developments in the immuno-metabolic mechanisms that govern disease initiation and progression. There is little doubt that the next most exciting therapy to combat cardiovascular disease will be based on targeting a biological pathway that will have been discussed during this conference. We will also review the pathways that govern inflammation resolution, their regulation by bioactive lipids, and how they can be harnessed to develop new therapeutic strategies to combat the disease. Finally, we will discuss existing and validated targets that are now in late-phase clinical trials. Key Sesseions Vascular Cell Activation and Dysfunction, Arterial monocytes/macrophages in health and disease, Innate immunity, NETosis, necroptosis, inflammasome, T Cell Immune Responses, B Cell Immune Responses, Adipose Tissue Inflammation, Insulin Resistance, Atherosclerosis, Resolution of Inflammation, Immunotherapies,