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The 30th Rencontres de Blois will be held on June 03 - 08, 2018 in the Château of Blois, in France-s Loire Valley. Focused on Particle Physics and Cosmology, it will emphasize the increasing interplay between high energy accelerator based physics and cosmology. The conference will consist of plenary sessions for invited in depth oral presentations (review talks and talks on specific specialised topics), and contributed papers, in the form of relatively short talks given in parallel sessions. Special emphasis being placed on active participation by younger researchers and post-docs. This will be the 30th meeting in this series of annual international multidisciplinary meetings, created in 1989 by Jean Trân Thanh Vân and which has in the past covered many topics in physics, astronomy and biology. All sessions take place in the Château of Blois, a beautiful renaissance castle which has housed many French kings, and notably François the 1st. Meals are served in the castle to all participants, in order to encourage interaction between scientists at all levels. Participation is limited to about 150 persons. The meeting will be articulated around the results and their impact on current theories from major new experimental and observational facilities. Below is the list of topics but the program is still open for new contributions : - the Standard Model of particle physics - the characterization of the Higgs boson - theories of and searches for physics beyond the Standard Model - heavy flavour physics - neutrino physics, including astrophysical neutrinos - astroparticle physics - dark matter, dark energy and recent advances in cosmology.