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Management problems of development of large-scale systems. Methods and tools of investment projects and programs management. Simulation and optimization. Management of fuel, power, infrastructure systems. Management of Transport systems. Aerospace complexes. Information support and software of management systems of large-scale production. Monitoring in the management of large-scale systems. Management of large scales systems advancement in healthcare, medico-biological systems and technologies. Methodology, methods, software and algorithmic support of Intellectual processing of large volumes of information.