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First organized by hemostasis pioneers Earl W. Davie and Oscar Ratnoff in 1973, the Hemostasis Gordon Research Conference (GRC) is considered the premiere small-format scientific meeting on the topics of blood coagulation, platelet biology, anticoagulant pathways, and associated diseases. The Hemostasis GRC brings together a community of scientists interested in the biology, biochemistry, and genetics of platelets and coagulation proteins; physicians involved in the treatment of bleeding and thrombotic diseases; and investigators from small and large pharmaceutical/biotechnology companies developing new therapeutics and diagnostics for disorders of the hemostatic system. Topics include novel and emerging aspects of hemostasis and thrombosis, as well as newly-identified roles for coagulation proteins, cells, and biophysical mechanisms in human disease. The 2018 Hemostasis GRC will be held July 29-Aug 3 at the Waterville Valley Conference Center, Waterville Valley, New Hampshire. The conference site provides a comfortable and inviting location for all participants, including a spacious conference center surrounded by the White Mountains of New Hampshire. The conference center has ~15,000 square feet of flexible, highly-functional space. Numerous recreational activities are available to participants including biking, hiking, golf, tennis, boating, swimming, scenic chair lift ride, and the Waterville Valley Recreation Center. Waterville Valley is only two hours north of Boston, making travel to and from this location convenient for attendees from the United States, Canada, and abroad. All accommodations are accessible to people with disabilities. A primary goal of the conference is for every attendee to participate as a speaker, discussion leader, or poster presenter. All applicants are encouraged to submit an abstract for presentation at one of the four scheduled poster sessions and consideration for an oral presentation at the Late-Breaking Topics session. Poster sessions are always well attended and provide a dedicated and highly-interactive forum for conversations among junior and senior investigators in the field. Afternoons are open for informal discussion among attendees, as well as leisure activities that enhance interactions, intellectual exchange, and foster new collaborations – a traditional and unique component of the Hemostasis GRC.