cancerresearch

Cancer Research

1 Years ago

Breakthrough in understanding Warsaw breakage syndrome: Unravelling the action of the DDX11/CHLR1 helicase enzyme in DNA repair

Researchers have uncovered a previously unknown function of the DDX11 helicase enzyme. Mutations in the gene which codes for DDX11 are known to be implicated in Warsaw Breakage Syndrome. They showed that DDX11 plays an important role in DNA repair, and functions as a backup to the Fanconi Anemia (FA) pathway, whose malfunction is associated with another life-debilitating condition.

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