cancerresearch

Cancer Research

2 Years ago
Scientists devise strategies to counteract T cell exhaustion in CAR T cancer therapies: Scientists show that deleting troublesome proteins in a mouse model can shrink tumors and prolong survival

Scientists devise strategies to counteract T cell exhaustion in CAR T cancer therapies: Scientists show that deleting troublesome proteins in a mouse model can shrink tumors and prolong survival

CAR T-cell therapies have saved lives in patients with blood cancers, but there has been a downside: T cells that enter solid tumors can stop working due to a phenomenon called T cell exhaustion. Now scientists have found a way of counteracting T cell exhaustion and making CAR T cell therapies more effective.

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