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Science of Life

2 Years ago

A quick path to antimalarial resistance: P. falciparum parasites can develop drug resistance by epigenetic changes in clag3 gene expression

Resistance to antimalarial drugs is thought to result mainly from changes in the parasite's genome. However, P. falciparum can also develop resistance to some antimalarial compounds by epigenetic changes, according to a new study. This is of concern because resistance acquired at the epigenetic level can arise quickly, even during the course of a single infection.

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