Dengue takes low and slow approach to replication
- January 15, 2018
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Dengue virus slowly takes over the endoplasmic reticulum, the production site for a subset of host proteins, and steers clear of the cytosol, the fluid-filled space where the majority of host cellular proteins are synthesized. Its viral RNA template is translated into protein in such an inefficient, lackadaisical manner that it doesn't trip alarms.