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On the origin of B1 cells
- February 16, 2019
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A new study may resolve a decades-old debate in immunology: researchers report that distinct progenitor cells are not required for the development of B1 cells. Instead, the team's experiments show that a B1-typical B-cell receptor can reprogram B2 cells into B1 cells, suggesting that B1 cells emerge as a consequence of their special B-cell receptors.